8UX1

Cryo-EM structure of Ran bound to RCC1 and the nucleosome core particle

Exp. Method EM
Resolution, Å 2.5
Release Date 2023-11-22
Update Date 2023-11-22
Authors Huang, S.K., Rubinstein, J.L., Kay, L.E.
Publication PMID:
doi
Related structures 8UX1
RCSB PDB 8UX1
EMDB EMD-42685
Q-score 0.609
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Drosophila melanogaster P02299
Distal A canonical H3 Drosophila melanogaster P02299
H4 Proximal F canonical H4 Drosophila melanogaster P84040
Distal B canonical H4 Drosophila melanogaster P84040
H2A Proximal G canonical H2A Drosophila melanogaster P84051
Distal C canonical H2A Drosophila melanogaster P84051
H2B Proximal H canonical H2B Drosophila melanogaster P02283
Distal D canonical H2B Drosophila melanogaster P02283
Other proteins:
Chain Name UID
K GTP-binding nuclear protein Ran P62826
L Regulator of chromosome condensation P18754
DNA:
Chain Variant Length
I 601 145
J 601 146

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.