8VOB

H3K36me3-modified nucleosome bound to PRC2_AJ1-450

Exp. Method EM
Resolution, Å 3.1
Release Date 2025-01-15
Update Date 2025-03-05
Authors Cookis, T., Lydecker, A., Sauer, P., Kasinath, V., Nogales, E.
doi 10.1038/s41594-024-01452-x
Publication PMID: 39774834
Related structures
RCSB PDB 8VOB
EMDB EMD-43373
Q-score 0.375
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal O canonical H3 Homo sapiens Q71DI3
Distal I canonical H3 Homo sapiens Q71DI3
H4 Proximal Q canonical H4 Homo sapiens P62805
Distal J canonical H4 Homo sapiens P62805
H2A Proximal R canonical H2A Homo sapiens P0C0S8
Distal K canonical H2A Homo sapiens P0C0S8
H2B Proximal S canonical H2B Xenopus laevis P02281
Distal M canonical H2B Xenopus laevis P02281
DNA:
Chain Variant Length
D 601 157
H 601 157

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.