8V6V

Cryo-EM structure of doubly-bound SNF2h-nucleosome complex

Exp. Method EM
Resolution, Å 2.8
Release Date 2024-03-20
Update Date 2024-03-20
Authors Chio, U.S., Palovcak, E., Smith, A.A.A., Autzen, H., Munoz, E.N., Yu, Z., Wang, F., Agard, D.A., Armache, J.P., Narlikar, G.J., Cheng, Y.
Publication PMID: 38472177
doi 10.1038/s41467-024-46178-y
Related structures 8V4Y
RCSB PDB 8V6V
EMDB EMD-43002
Q-score 0.477
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
W SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 O60264
X SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 O60264
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.