8T3Y

Structure of Bre1-nucleosome complex - state1

Exp. Method EM
Resolution, Å 3.47
Release Date 2023-10-18
Update Date 2023-11-22
Authors Zhao, F., Hicks, C.W., Wolberger, C.
Publication PMID: 37872231
doi 10.1038/s41594-023-01137-x
RCSB PDB 8T3Y
EMDB EMD-41016
Q-score 0.503
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K E3 ubiquitin-protein ligase BRE1 Q07457
L E3 ubiquitin-protein ligase BRE1 Q07457
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.