8SPS

High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b

Exp. Method EM
Resolution, Å 3
Release Date 2023-06-28
Update Date 2024-11-13
Authors Guan, R., Lian, T., Zhou, B.R., Wheeler, D., Bai, Y.
doi 10.1016/j.molcel.2023.05.030
Publication PMID: 37327775
Related structures
RCSB PDB 8SPS
EMDB EMD-40683
Q-score 0.434
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens Q16777
Distal G canonical H2A Homo sapiens Q16777
H2B Proximal D canonical H2B Homo sapiens Q16778
Distal H canonical H2B Homo sapiens Q16778
Other proteins:
Chain Name UID
K ScFv NA
L Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 Q01860
M Maltodextrin-binding protein,POU domain, class 5, transcription factor 1 Q01860
N ScFv NA
DNA:
Chain Variant Length
I None 147
J None 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.