8QKV

SWR1-nucleosome complex in configuration 2

Exp. Method EM
Resolution, Å 4.7
Release Date 2024-10-02
Update Date 2024-12-18
Authors Girvan, P., Jalal, A.S.B., McCormack, E.A., Skehan, M.T., Knight, C.L., Wigley, D.B., Rueda, D.S.
doi 10.1038/s41586-024-08152-y
Publication PMID: 39506114
Related structures
RCSB PDB 8QKV
EMDB EMD-18472
Q-score 0.185
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Saccharomyces cerevisiae S288C P61830
Distal B canonical H3 Saccharomyces cerevisiae S288C P61830
H4 Proximal D canonical H4 Saccharomyces cerevisiae S288C P02309
Distal C canonical H4 Saccharomyces cerevisiae S288C P02309
H2A Proximal E H2A.X Saccharomyces cerevisiae S288C P04912
Distal F H2A.X Saccharomyces cerevisiae S288C P04912
H2B Proximal G canonical H2B Saccharomyces cerevisiae S288C P02293
Distal H canonical H2B Saccharomyces cerevisiae S288C P02293
Other proteins:
Chain Name UID
M Helicase SWR1 Q05471
R Actin-like protein ARP6 Q12509
S Vacuolar protein sorting-associated protein 71 Q03433
T RuvB-like protein 1 Q03940
U RuvB-like protein 2 Q12464
V RuvB-like protein 1 Q03940
W RuvB-like protein 2 Q12464
X RuvB-like protein 1 Q03940
Y RuvB-like protein 2 Q12464
Z Vacuolar protein sorting-associated protein 72 Q03388
DNA:
Chain Variant Length
I 601 194
J 601 194

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.