8PKJ

Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5

Exp. Method EM
Resolution, Å 2.5
Release Date 2024-02-28
Update Date 2024-03-06
Authors Kobayashi, W., Sappler, A.H., Bollschweiler, D., Kummecke, M., Basquin, J., Arslantas, E.N., Ruangroengkulrith, S., Hornberger, R., Duderstadt, K., Tachibana, K.
Publication PMID: 38409506
doi 10.1038/s41594-024-01239-0
RCSB PDB 8PKJ
EMDB EMD-17741
Q-score 0.6
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A H3.3 Mus musculus A0A7L1D652
Distal E H3.3 Mus musculus A0A7L1D652
H4 Proximal B canonical H4 Mus musculus A0A3Q2Z0K7
Distal F canonical H4 Mus musculus A0A3Q2Z0K7
H2A Proximal C canonical H2A Mus musculus B2RVF0
Distal G canonical H2A Mus musculus B2RVF0
H2B Proximal D canonical H2B Mus musculus A0A2J8S4Y0
Distal H canonical H2B Mus musculus A0A2J8S4Y0
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.