8PKI

Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5

Exp. Method EM
Resolution, Å 2.58
Release Date 2024-02-28
Update Date 2024-03-06
Authors Kobayashi, W., Sappler, A.H., Bollschweiler, D., Kummecke, M., Basquin, J., Arslantas, E.N., Ruangroengkulrith, S., Hornberger, R., Duderstadt, K., Tachibana, K.
Publication PMID: 38409506
doi 10.1038/s41594-024-01239-0
RCSB PDB 8PKI
EMDB EMD-17740
Q-score 0.572
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A H3.3 Mus musculus P84244
Distal E H3.3 Mus musculus P84244
H4 Proximal B canonical H4 Mus musculus P62806
Distal F canonical H4 Mus musculus P62806
H2A Proximal C canonical H2A Mus musculus B2RVF0
Distal G canonical H2A Mus musculus B2RVF0
H2B Proximal D canonical H2B Mus musculus Q6ZWY9
Distal H canonical H2B Mus musculus Q6ZWY9
Other proteins:
Chain Name UID
K Nuclear receptor subfamily 5 group A member 2 O00482
DNA:
Chain Variant Length
I 601 137
J 601 138

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.