8OX1

Structure of TRF1core in complex with telomeric nucleosome

Exp. Method EM
Resolution, Å 2.7
Release Date 2023-08-30
Update Date 2023-09-06
Authors Hu, H., van Roon, A.M., Ghanim, G.E., Ahsan, B., Oluwole, A.O., Peak-Chew, S.Y., Robinson, C.V., Nguyen, T.H.D.
Publication PMID: 37624885
doi 10.1126/sciadv.adi4148
RCSB PDB 8OX1
EMDB EMD-17252
Q-score 0.579
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens Q93077
Distal C canonical H2A Homo sapiens Q93077
H2B Proximal H canonical H2B Homo sapiens P62807
Distal D canonical H2B Homo sapiens P62807
Other proteins:
Chain Name UID
L Telomeric repeat-binding factor 1 P54274
M Telomeric repeat-binding factor 1 P54274
DNA:
Chain Variant Length
I telomeric_human 145
J telomeric_human 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.