8J6T

Cryo-EM structure of the double CAF-1 bound right-handed Di-tetrasome

Exp. Method EM
Resolution, Å 6.6
Release Date 2023-08-16
Update Date 2023-09-06
Authors Liu, C.P., Yu, Z., Xiong, J., Hu, J., Song, A., Ding, D., Yu, C., Yang, N., Wang, M., Yu, J., Hou, P., Zeng, K., Li, Z., Zhang, Z., Zhang, X., Li, W., Zhang, Z., Zhu, B., Li, G., Xu, R.M.
Publication PMID: 37616371
doi 10.1126/science.add8673
RCSB PDB 8J6T
EMDB EMD-36014
Q-score 0.166
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal C canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal D canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
Other proteins:
Chain Name UID
K Chromatin assembly factor 1 subunit A Q13111
L Chromatin assembly factor 1 subunit B Q13112
M Chromatin assembly factor 1 subunit A Q13111
N Chromatin assembly factor 1 subunit B Q13112
DNA:
Chain Variant Length
I 601 92
J 601 91

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Analysis fail
Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.