8IEG

Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex

Exp. Method EM
Resolution, Å 3.44
Release Date 2023-09-06
Update Date 2023-09-20
Authors Deng, Z., Ai, H., Sun, M., Tong, Z., Du, Y., Qu, Q., Zhang, L., Xu, Z., Tao, S., Shi, Q., Li, J.B., Pan, M., Liu, L.
Publication PMID: 37633270
doi 10.1016/j.molcel.2023.08.001
RCSB PDB 8IEG
EMDB EMD-35381
Q-score 0.393
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal K canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal L canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P04908
Distal C canonical H2A Homo sapiens P04908
H2B Proximal H canonical H2B Homo sapiens O60814
Distal D canonical H2B Homo sapiens O60814
Other proteins:
Chain Name UID
A E3 ubiquitin-protein ligase BRE1 Q07457
B E3 ubiquitin-protein ligase BRE1 Q07457
R Ubiquitin-conjugating enzyme E2 2 P06104
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.