8GUI

Bre1-nucleosome complex (Model I)

Exp. Method EM
Resolution, Å 2.81
Release Date 2023-09-20
Update Date 2024-04-03
Authors Onishi, S., Uchiyama, K., Sato, K., Okada, C., Kobayashi, S., Hamada, K., Nishizawa, T., Nureki, O., Ogata, K., Sengoku, T.
Publication PMID: 38519511
doi 10.1038/s41467-024-46910-8
Related structures 8GUJ, 8GUK
RCSB PDB 8GUI
EMDB EMD-34274
Q-score 0.532
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P0C0S8
Distal C canonical H2A Homo sapiens P0C0S8
H2B Proximal H canonical H2B Homo sapiens P06899
Distal D canonical H2B Homo sapiens P06899
Other proteins:
Chain Name UID
K E3 ubiquitin-protein ligase BRE1A Q5VTR2
L E3 ubiquitin-protein ligase BRE1B O75150
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.