8G88

Human Oct4 bound to nucleosome with human nMatn1 sequence

Exp. Method EM
Resolution, Å 2.3
Release Date 2023-03-22
Update Date 2024-06-19
Authors Sinha, K.K., Bilokapic, S., Du, Y., Malik, D., Halic, M.
doi 10.1038/s41586-023-06112-6
Publication PMID: 37225990
Related structures 8G86, 8G87, 8G8B, 8G8E, 8G8G
RCSB PDB 8G88
EMDB EMD-29843
Q-score 0.199
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis Q6AZJ8
Distal G canonical H2A Xenopus laevis Q6AZJ8
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
X POU domain, class 5, transcription factor 1 Q01860
DNA:
Chain Variant Length
I None 168
J None 168

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.