8COM

Structure of the Nucleosome Core Particle from Trypanosoma brucei

Exp. Method EM
Resolution, Å 3.3
Release Date 2023-07-12
Update Date 2023-09-06
Authors Deak, G., Wapenaar, H., Sandoval, G., Chen, R., Taylor, M.R.D., Burdett, H., Watson, J.A., Tuijtel, M.W., Webb, S., Wilson, M.D.
doi 10.1093/nar/gkad577
Publication PMID: 37427792
Related structures
RCSB PDB 8COM
EMDB EMD-16777
Q-score 0.439
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Trypanosoma brucei brucei TREU927 Q4GYX7
Distal A canonical H3 Trypanosoma brucei brucei TREU927 Q4GYX7
H4 Proximal F canonical H4 Trypanosoma brucei brucei TREU927 Q57Z31
Distal B canonical H4 Trypanosoma brucei brucei TREU927 Q57Z31
H2A Proximal G canonical H2A Trypanosoma brucei brucei TREU927 Q57YA3
Distal C canonical H2A Trypanosoma brucei brucei TREU927 Q57YA3
H2B Proximal H canonical H2B Trypanosoma brucei brucei TREU927 Q389T1
Distal D canonical H2B Trypanosoma brucei brucei TREU927 Q389T1
DNA:
Chain Variant Length
I 601 127
J 601 127

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score Local Resolution

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.