7YI1

Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome

Exp. Method EM
Resolution, Å 2.8
Release Date 2023-06-14
Update Date 2023-08-30
Authors Guan, H., Wang, P., Zhang, P., Ruan, C., Ou, Y., Peng, B., Zheng, X., Lei, J., Li, B., Yan, C., Li, H.
Publication PMID: 37468628
doi 10.1038/s41586-023-06349-1
Related structures 7YI0
RCSB PDB 7YI1
EMDB EMD-33848
Q-score 0.572
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Chromatin modification-related protein EAF3 Q12432
L Chromatin modification-related protein EAF3 Q12432
DNA:
Chain Variant Length
I 601 151
J 601 151

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score Local Resolution

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.