7Y8R

The nucleosome-bound human PBAF complex

Exp. Method EM
Resolution, Å 4.4
Release Date 2022-12-07
Update Date 2022-12-21
Authors Wang, L., Yu, J., Yu, Z., Wang, Q., Li, W., Ren, Y., Chen, Z., He, S., Xu, Y.
Publication PMID: 36496390
doi 10.1038/s41467-022-34859-5
RCSB PDB 7Y8R
EMDB EMD-33684
Q-score 0.172
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens Q93077
Distal G canonical H2A Homo sapiens Q93077
H2B Proximal D canonical H2B Homo sapiens P62807
Distal H canonical H2B Homo sapiens P62807
Other proteins:
Chain Name UID
I Transcription activator BRG1 P51532
J ACTB protein (Fragment) P60709
K Actin-like protein 6A O96019
L AT-rich interactive domain-containing protein 2 Q68CP9
M SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Q12824
N SWI/SNF complex subunit SMARCC2 Q8TAQ2
O SWI/SNF complex subunit SMARCC2 Q8TAQ2
P SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 Q96GM5
Q SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Q969G3
R PHD finger protein 10 Q8WUB8
S Bromodomain-containing protein 7 Q9NPI1
U Protein polybromo-1 Q86U86
DNA:
Chain Variant Length
X 601 165
Y 601 165

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.