| Exp. Method | EM |
|---|---|
| Resolution, Å | 3.9 |
| Release Date | 2022-09-07 |
| Update Date | 2022-10-19 |
| Authors | Ehara, H., Kujirai, T., Shirouzu, M., Kurumizaka, H., Sekine, S.I. |
| Publication | PMID: 35981082 |
| doi | 10.1126/science.abp9466 |
| RCSB PDB | 7XTD |
| EMDB | EMD-33447 |
| Q-score | 0.221 |
| Side | Chain | HistoneDB Variant | Taxa | UID | |
|---|---|---|---|---|---|
| H3 | Proximal | e | H3.3 | Homo sapiens | P84243 |
| Distal | a | H3.3 | Homo sapiens | P84243 | |
| H4 | Proximal | f | canonical H4 | Homo sapiens | P62805 |
| Distal | b | canonical H4 | Homo sapiens | P62805 | |
| H2A | Proximal | g | canonical H2A | Homo sapiens | P04908 |
| Distal | c | canonical H2A | Homo sapiens | P04908 | |
| H2B | Proximal | h | canonical H2B | Homo sapiens | P06899 |
| Distal | d | canonical H2B | Homo sapiens | P06899 |
| Chain | Name | UID |
|---|---|---|
| A | DNA-directed RNA polymerase subunit | C4R4Y0 |
| B | DNA-directed RNA polymerase subunit beta | C4QZQ7 |
| C | RNA polymerase II third largest subunit B44, part of central core | C4R7L2 |
| D | RNA polymerase II subunit B32 | C4R2U9 |
| E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 | C4R3P8 |
| F | RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III | C4R1V1 |
| G | RNA polymerase II subunit | C4R9A1 |
| H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 | C4R273 |
| I | DNA-directed RNA polymerase subunit | F2QPE6 |
| J | RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III | C4R009 |
| K | RNA polymerase II subunit B12.5 | C4R3Z5 |
| L | RNA polymerase subunit ABC10-alpha | F2QMI1 |
| M | Transcription elongation factor 1 homolog | C4QZ45 |
| V | Transcription elongation factor SPT4 | C4R0E6 |
| W | Transcription elongation factor SPT5 | C4R370 |
| j | FACT complex subunit | C4QYQ8 |
| k | FACT complex subunit POB3 | F2QNN8 |
| m | Transcription elongation factor Spt6 | C4R7H2 |
| n | Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II | C4R7L8 |
| q | Component of the Paf1p complex | C4R6B2 |
| r | RNAPII-associated chromatin remodeling Paf1 complex subunit | F2QQ42 |
| u | Leo1 | C4R3K1 |
| v | RNAP II-associated protein | C4R997 |
| x | Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p | C4R1E6 |
| Chain | Variant | Length |
|---|---|---|
| N | 601_modified | 112 |
| T | 601_modified | 123 |
H3
H4
H2A
H2B
DNA
Other