7XD1

cryo-EM structure of unmodified nucleosome

Exp. Method EM
Resolution, Å 3.2
Release Date 2022-04-20
Update Date 2022-09-07
Authors Ai, H., Sun, M., Liu, A., Sun, Z., Liu, T., Cao, L., Liang, L., Qu, Q., Li, Z., Deng, Z., Tong, Z., Chu, G., Tian, X., Deng, H., Zhao, S., Li, J.B., Lou, Z., Liu, L.
Publication PMID: 35739357
doi 10.1038/s41589-022-01067-7
RCSB PDB 7XD1
EMDB EMD-33132
Q-score 0.558
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P04908
Distal C canonical H2A Homo sapiens P04908
H2B Proximal H canonical H2B Homo sapiens O60814
Distal D canonical H2B Homo sapiens O60814
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.