7X3V

Cryo-EM structure of IOC3-N2 nucleosome

Exp. Method EM
Resolution, Å 3.09
Release Date 2023-09-20
Update Date 2024-02-28
Authors Li, L., Chen, K., Sia, Y., Hu, P., Ye, Y., Chen, Z.
Publication PMID: 38177688
doi 10.1038/s41594-023-01174-6
RCSB PDB 7X3V
EMDB EMD-32994
Q-score 0.502
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
U ISWI one complex protein 3 P43596
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.