7VVU

NuA4 HAT module bound to the nucleosome

Exp. Method EM
Resolution, Å 3.4
Release Date 2022-08-10
Update Date 2022-11-16
Authors Qu, K., Chen, K., Wang, H., Li, X., Chen, Z.
Publication PMID: 36198799
doi 10.1038/s41586-022-05303-x
RCSB PDB 7VVU
EMDB EMD-32148
Q-score 0.314
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal O canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal Q canonical H4 Xenopus laevis P62799
H2A Proximal N canonical H2A Xenopus laevis P06897
Distal S canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal U canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
P Histone acetyltransferase ESA1 Q08649
T Enhancer of polycomb-like protein 1 P43572
V Chromatin modification-related protein YNG2 P38806
X Enhancer of polycomb-like protein 1 P43572
Y Chromatin modification-related protein EAF6 P47128
DNA:
Chain Variant Length
I 601 179
W 601 180

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.