7VDV

The overall structure of human chromatin remodeling PBAF-nucleosome complex

Exp. Method EM
Resolution, Å 3.4
Release Date 2022-05-18
Update Date 2022-05-18
Authors Yuan, J.J., Chen, K.J., Zhang, W.B., Chen, Z.C.
Publication PMID: 35477757
doi 10.1038/s41586-022-04658-5
RCSB PDB 7VDV
EMDB EMD-31926
Q-score 0.315
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal K canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
A Isoform 2 of Transcription activator BRG1 P51532
N Actin-like protein 6A O96019
P Actin, cytoplasmic 1 P60709
Q AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2 Q68CP9
R PHD finger protein 10 Q8WUB8
T Isoform 2 of Bromodomain-containing protein 7 Q9NPI1
V SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Q12824
W SWI/SNF complex subunit SMARCC2 Q8TAQ2
X SWI/SNF complex subunit SMARCC2 Q8TAQ2
Y SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 Q96GM5
Z SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 Q969G3
a Protein polybromo-1 Q86U86
DNA:
Chain Variant Length
I 601 135
J 601 137

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.