7VBM

The mouse nucleosome structure containing H3mm18 aided by PL2-6 scFv

Exp. Method EM
Resolution, Å 3.4
Release Date 2022-01-19
Update Date 2022-02-16
Authors Hirai, S., Tomimatsu, K., Miyawaki-Kuwakado, A., Takizawa, Y., Komatsu, T., Tachibana, T., Fukushima, Y., Takeda, Y., Negishi, L., Kujirai, T., Koyama, M., Ohkawa, Y., Kurumizaka, H.
Publication PMID: 34929737
doi 10.1093/nar/gkab1137
Related structures 7DBH
RCSB PDB 7VBM
EMDB EMD-31882
Q-score 0.506
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A H3.3 Mus musculus None
Distal E H3.3 Mus musculus None
H4 Proximal B canonical H4 Mus musculus P62806
Distal F canonical H4 Mus musculus P62806
H2A Proximal C canonical H2A Mus musculus C0HKE1
Distal G canonical H2A Mus musculus C0HKE1
H2B Proximal D canonical H2B Mus musculus Q9D2U9
Distal H canonical H2B Mus musculus Q9D2U9
DNA:
Chain Variant Length
I 601 126
J 601 126

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.