7U51

Nucleosome core particle with AP-site at SHL-6

Exp. Method EM
Resolution, Å 3.1
Release Date 2022-09-07
Update Date 2022-10-05
Authors Weaver, T.M., Hoitsma, N.M., Spencer, J.J., Gakhar, L., Schnicker, N.J., Freudenthal, B.D.
Publication PMID: 36104361
doi 10.1038/s41467-022-33057-7
RCSB PDB 7U51
EMDB EMD-26337
Q-score 0.537
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens Q71DI3
Distal E canonical H3 Homo sapiens Q71DI3
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens P0C0S8
Distal G canonical H2A Homo sapiens P0C0S8
H2B Proximal D canonical H2B Homo sapiens P62807
Distal H canonical H2B Homo sapiens P62807
DNA:
Chain Variant Length
I 601 144
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.