7TAN

Structure of VRK1 C-terminal tail bound to nucleosome core particle

Exp. Method EM
Resolution, Å 3
Release Date 2022-05-04
Update Date 2024-02-28
Authors Budziszewski, G.R., Zhao, Y., Spangler, C.J., Kedziora, K.M., Williams, M.R., Azzam, D.N., Skrajna, A., Koyama, Y., Cesmat, A.P., Simmons, H.C., Arteaga, E.C., Strauss, J.D., Kireev, D., McGinty, R.K.
Publication PMID: 35390161
doi 10.1093/nar/gkac198
RCSB PDB 7TAN
EMDB EMD-25777
Q-score 0.56
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens Q71DI3
Distal A canonical H3 Homo sapiens Q71DI3
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P0C0S8
Distal C canonical H2A Homo sapiens P0C0S8
H2B Proximal H canonical H2B Homo sapiens P62807
Distal D canonical H2B Homo sapiens P62807
Other proteins:
Chain Name UID
K Serine/threonine-protein kinase VRK1 Q99986
L Serine/threonine-protein kinase VRK1 Q99986
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.