7PFF

Nucleosome 3 of the 4x197 nucleosome array containing H1

Exp. Method EM
Resolution, Å 4.3
Release Date 2022-08-03
Update Date 2024-07-17
Authors Dombrowski, M., Engeholm, M., Dienemann, C., Dodonova, S., Cramer, P.
doi 10.1038/s41594-022-00768-w
Publication PMID: 35581345
Related structures
RCSB PDB 7PFF
EMDB EMD-13374
Q-score 0.221
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal O canonical H3 Homo sapiens Q71DI3
Distal K canonical H3 Homo sapiens Q71DI3
H4 Proximal P canonical H4 Homo sapiens P62805
Distal L canonical H4 Homo sapiens P62805
H2A Proximal Q canonical H2A Homo sapiens P04908
Distal M canonical H2A Homo sapiens P04908
H2B Proximal R canonical H2B Homo sapiens O60814
Distal N canonical H2B Homo sapiens O60814
DNA:
Chain Variant Length
I 601 167
J 601 167

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

-60-40-200204060-40-200204060Coordinate X, ACoordinate Y, AH3H4H2AH2BDNA
Nucleosome reference frame definition

DNA relative twist and local base step parameters

GGCCGCCATACTGGAGAATCCCGGTGCCGAGGCCGCTCAATTGGTCGTAGACAGCTCTAGCACCGCTTAAACGCACGTACGCGCTGTCCCCCGCGTTTTAACCGCCAAGGGGATTACTCCCTAGTCTCCAGGCACGTGTCAGATATATACATCCTGTCATGTAAGTA-1000100DNA relative twist, °-80-70-60-50-40-30-20-1001020304050607080rTwrTwfTA pairTA stepYR step
Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.