7OH9

Nucleosome with TBP and TFIIA bound at SHL -6

Exp. Method EM
Resolution, Å 3
Release Date 2021-07-28
Update Date 2021-08-04
Authors Wang, H., Xiong, L., Cramer, P.
Publication PMID: 34301908
doi 10.1073/pnas.2108859118
RCSB PDB 7OH9
EMDB EMD-12897
Q-score 0.49
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K TATA-binding protein P13393
L Transcription initiation factor IIA large subunit P32773
M Transcription initiation factor IIA subunit 2 P32774
DNA:
Chain Variant Length
I 601 145
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.