7M1X

Cryo-EM Structure of Nucleosome containing mouse histone variant H2A.Z

Exp. Method EM
Resolution, Å 3.7
Release Date 2021-09-29
Update Date 2024-11-13
Authors Lewis, T.S., Sokolova, V., Jung, H., Ng, H., Tan, D.
doi 10.1093/nar/gkab907
Publication PMID: 34643712
Related structures
RCSB PDB 7M1X
EMDB EMD-23626
Q-score 0.391
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P02302
Distal A canonical H3 Xenopus laevis P02302
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G H2A.Z Mus musculus P0C0S6
Distal C H2A.Z Mus musculus P0C0S6
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
DNA:
Chain Variant Length
I 601 136
J 601 136

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

-40-2002040-40-2002040Coordinate X, ACoordinate Y, AH3H4H2AH2BDNA
Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.