7K60

Cryo-EM structure of a chromatosome containing human linker histone H1.10

Exp. Method EM
Resolution, Å 3.12
Release Date 2020-11-25
Update Date 2024-03-06
Authors Zhou, B.R., Feng, H., Kale, S., Fox, T., Khant, H., de Val, N., Ghirlando, R., Panchenko, A.R., Bai, Y.
Publication PMID: 33238161
doi 10.1016/j.molcel.2020.10.038
Related structures 7K5Y, 7K5X
RCSB PDB 7K60
EMDB EMD-22685
Q-score 0.435
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P04908
Distal C canonical H2A Homo sapiens P04908
H2B Proximal H canonical H2B Homo sapiens P06899
Distal D canonical H2B Homo sapiens P06899
H1:
Chain HistoneDB Variant UID
U H1.10 Q92522
Other proteins:
Chain Name UID
M scFv20 NA
N scFv20 NA
DNA:
Chain Variant Length
I 601 197
J 601 197

H3

H4

H2A

H2B

H1

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.