7EGP

The structure of SWI/SNF-nucleosome complex

Exp. Method EM
Resolution, Å 6.9
Release Date 2022-01-12
Update Date 2022-01-12
Authors He, Z.Y., Chen, K.J., Ye, Y.P., Chen, Z.C.
Publication PMID: 33907182
doi 10.1038/s41421-021-00262-5
RCSB PDB 7EGP
EMDB EMD-31137
Q-score 0.105
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal O canonical H3 Xenopus laevis P84233
Distal S canonical H3 Xenopus laevis P84233
H4 Proximal P canonical H4 Xenopus laevis P62799
Distal T canonical H4 Xenopus laevis P62799
H2A Proximal Q canonical H2A Xenopus laevis Q6AZJ8
Distal U canonical H2A Xenopus laevis Q6AZJ8
H2B Proximal R canonical H2B Xenopus laevis P02281
Distal V canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
A Transcription regulatory protein SNF2 P22082
B SWI/SNF chromatin-remodeling complex subunit SWI1 P09547
C SWI/SNF chromatin-remodeling complex subunit SNF5 P18480
D SWI/SNF complex subunit SWI3 P32591
E SWI/SNF complex subunit SWI3 P32591
H Transcription regulatory protein SNF12 P53628
I Transcription regulatory protein SNF6 P18888
J SWI/SNF global transcription activator complex subunit SWP82 P43554
L Regulator of Ty1 transposition protein 102 P53330
M Actin-related protein 7 Q12406
N Actin-like protein ARP9 Q05123
DNA:
Chain Variant Length
W 601 166
X 601 166

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.