7EA5

Yeast Set2 bound to a nucleosome containing oncohistone mutations

Exp. Method EM
Resolution, Å 3.3
Release Date 2021-07-14
Update Date 2021-07-14
Authors Liu, Y., Zhang, Y., Xue, H., Cao, M., Bai, G., Mu, Z., Yao, Y., Sun, S., Fang, D., Huang, J.
Publication PMID: 33972509
doi 10.1038/s41421-021-00261-6
RCSB PDB 7EA5
EMDB EMD-31039
Q-score 0.473
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis Q6AZJ8
Distal G canonical H2A Xenopus laevis Q6AZJ8
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Histone-lysine N-methyltransferase, H3 lysine-36 specific P46995
DNA:
Chain Variant Length
I 601 145
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.