7DBP

Linker histone defines structure and self-association behaviour of the 177 bp human chromosome

Exp. Method EM
Resolution, Å 4.5
Release Date 2020-12-23
Update Date 2024-03-27
Authors Wang, S., Vogirala, V.K., Soman, A., Berezhnoy, N.V., Liu, Z.B., Wong, A.S.W., Korolev, N., Su, C.J., Sandin, S., Nordenskiold, L.
doi 10.1038/s41598-020-79654-8
Publication PMID: 33432055
Related structures
RCSB PDB 7DBP
EMDB EMD-30161
Q-score 0.246
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens P04908
Distal G canonical H2A Homo sapiens P04908
H2B Proximal D canonical H2B Homo sapiens O60814
Distal H canonical H2B Homo sapiens O60814
H1:
Chain HistoneDB Variant UID
K H1.0 P07305
DNA:
Chain Variant Length
I 601 175
J 601 175

H3

H4

H2A

H2B

H1

DNA

Other


Aligned nucleosome coordinates

-60-40-200204060-40-20020406080Coordinate X, ACoordinate Y, AH3H4H2AH2BDNA
Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.