7BWD

Structure of Dot1L-H2BK34ub Nucleosome Complex

Exp. Method EM
Resolution, Å 4.32
Release Date 2021-04-14
Update Date 2021-04-14
Authors Liu, L., Lou, Z.Y., Ai, H.S., Cao, L.
Publication PMID:
doi
RCSB PDB 7BWD
EMDB EMD-30232
Q-score 0.332
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Homo sapiens P68431
Distal A canonical H3 Homo sapiens P68431
H4 Proximal F canonical H4 Homo sapiens P62805
Distal B canonical H4 Homo sapiens P62805
H2A Proximal G canonical H2A Homo sapiens P04908
Distal C canonical H2A Homo sapiens P04908
H2B Proximal H canonical H2B Homo sapiens O60814
Distal D canonical H2B Homo sapiens O60814
Other proteins:
Chain Name UID
K Histone-lysine N-methyltransferase, H3 lysine-79 specific Q8TEK3
L Ubiquitin P62979
M Ubiquitin P62979
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.