6Z6P

HDAC-PC-Nuc

Exp. Method EM
Resolution, Å 4.43
Release Date 2021-02-17
Update Date 2021-02-17
Authors Lee, J.H., Bollschweiler, D., Schafer, T., Huber, R.
Publication PMID: 33523989
doi 10.1126/sciadv.abd4413
RCSB PDB 6Z6P
EMDB EMD-11102
Q-score 0.189
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis Q6AZJ8
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Histone deacetylase HDA1 P53973
L Histone deacetylase HDA1 P53973
M HDA1 complex subunit 3,HDA1 complex subunit 3 Q06623
N HDA1 complex subunit 2 Q06629
DNA:
Chain Variant Length
I 601 145
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.