6UPK

Structure of FACT_subnucleosome complex 1

Exp. Method EM
Resolution, Å 4.9
Release Date 2019-12-11
Update Date 2024-03-20
Authors Liu, Y., Zhou, K., Zhang, N., Wei, H., Tan, Y.Z., Zhang, Z., Carragher, B., Potter, C.S., D'Arcy, S., Luger, K.
Publication PMID: 31775157
doi 10.1038/s41586-019-1820-0
RCSB PDB 6UPK
EMDB EMD-20840
Q-score 0.203
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens Q93077
H2B Proximal D canonical H2B Homo sapiens P62807
Other proteins:
Chain Name UID
G FACT complex subunit SPT16 Q9Y5B9
H FACT complex subunit SSRP1 Q08945
DNA:
Chain Variant Length
I 601_modified 72
J 601_modified 72

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.