6TDA

Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome

Exp. Method EM
Resolution, Å 15
Release Date 2020-03-18
Update Date 2024-03-27
Authors Wagner, F.R., Dienemann, C., Wang, H., Stutzer, A., Tegunov, D., Urlaub, H., Cramer, P.
Publication PMID: 32188943
doi 10.1038/s41586-020-2088-0
RCSB PDB 6TDA
EMDB EMD-10465
Q-score 0.081
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Chromatin structure-remodeling complex subunit SFH1 Q06168
L Chromatin structure-remodeling complex protein RSC8 P43609
M Chromatin structure-remodeling complex subunit RSC7 P32832
N Chromatin structure-remodeling complex subunit RSC9 Q03124
O Chromatin structure-remodeling complex protein RSC6 P25632
P Chromatin structure-remodeling complex protein RSC58 Q07979
Q High temperature lethal protein 1 Q9URQ5
R Chromatin structure-remodeling complex subunit RSC4 Q02206
S Nuclear protein STH1/NPS1 P32597
T Actin-related protein 7 Q12406
U Actin-like protein ARP9 Q05123
V Regulator of Ty1 transposition protein 102 P53330
DNA:
Chain Variant Length
I 601 160
J 601 160

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.