6T9L

SAGA DUB module bound to a ubiqitinated nucleosome

Exp. Method EM
Resolution, Å 3.6
Release Date 2020-01-29
Update Date 2020-02-19
Authors Wang, H., Dienemann, C., Stutzer, A., Urlaub, H., Cheung, A.C.M., Cramer, P.
Publication PMID: 31969703
doi 10.1038/s41586-020-1933-5
RCSB PDB 6T9L
EMDB EMD-10415
Q-score 0.394
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Ubiquitin carboxyl-terminal hydrolase 8 P50102
L Transcription and mRNA export factor SUS1 Q6WNK7
M SAGA-associated factor 11 Q03067
N SAGA-associated factor 73 P53165
O Polyubiquitin-C P0CG48
DNA:
Chain Variant Length
I 601 145
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.