6SEF

Class2C : CENP-A nucleosome in complex with CENP-C central region

Exp. Method EM
Resolution, Å 3.7
Release Date 2019-08-14
Update Date 2019-11-06
Authors Ali-Ahmad, A., Bilokapic, S., Schafer, I.B., Halic, M., Sekulic, N.
Publication PMID: 31475439
doi 10.15252/embr.201948913
RCSB PDB 6SEF
EMDB EMD-10154
Q-score 0.372
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A cenH3 Homo sapiens P49450
Distal E cenH3 Homo sapiens P49450
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens Q6FI13
Distal G canonical H2A Homo sapiens Q6FI13
H2B Proximal D canonical H2B Homo sapiens P62807
Distal H canonical H2B Homo sapiens P62807
Other proteins:
Chain Name UID
V Centromere protein C Q03188
DNA:
Chain Variant Length
I 601 145
J 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.