6PWE

Cryo-EM structure of nucleosome core particle

Exp. Method EM
Resolution, Å 3.95
Release Date 2019-08-21
Update Date 2024-03-20
Authors Chittori, S., Hong, J., Bai, Y., Subramaniam, S.
Publication PMID: 31402386
doi 10.1093/nar/gkz670
RCSB PDB 6PWE
EMDB EMD-20506
Q-score 0.409
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Drosophila melanogaster P02299
Distal A canonical H3 Drosophila melanogaster P02299
H4 Proximal F canonical H4 Drosophila melanogaster P84040
Distal B canonical H4 Drosophila melanogaster P84040
H2A Proximal G canonical H2A Drosophila melanogaster P84051
Distal C canonical H2A Drosophila melanogaster P84051
H2B Proximal H canonical H2B Drosophila melanogaster P02283
Distal D canonical H2B Drosophila melanogaster P02283
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.