6OM3

Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle

Exp. Method X-ray
Resolution, Å 3.3
Release Date 2019-07-10
Update Date 2023-10-11
Authors De Ioannes, P., Leon, V.A., Kuang, Z., Wang, M., Boeke, J.D., Hochwagen, A., Armache, K.J.
Publication PMID: 31263106
doi 10.1038/s41467-019-10609-y
RCSB PDB 6OM3
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Origin recognition complex subunit 1 P54784
L Origin recognition complex subunit 1 P54784
W Origin recognition complex subunit 1 P54784
X Origin recognition complex subunit 1 P54784
DNA:
Chain Variant Length
I 601 146
J 601 147
U 601 146
V 601 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.