6M4H

Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2

Exp. Method EM
Resolution, Å 3.9
Release Date 2020-09-23
Update Date 2024-03-27
Authors Zhou, M., Dai, L., Li, C., Shi, L., Huang, Y., Guo, Z., Wu, F., Zhu, P., Zhou, Z.
Publication PMID: 33073403
doi 10.15252/embj.2020105907
RCSB PDB 6M4H
EMDB EMD-30078
Q-score 0.365
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C H2A.B Homo sapiens P0C5Z0
Distal G H2A.B Homo sapiens P0C5Z0
H2B Proximal D canonical H2B Homo sapiens Q16778
Distal H canonical H2B Homo sapiens Q16778
DNA:
Chain Variant Length
I 601 103
J 601 103

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.