6K1K

Human nucleosome core particle with H2A.X S139E variant

Exp. Method X-ray
Resolution, Å 2.2
Release Date 2020-01-15
Update Date 2023-11-22
Authors Sharma, D., De Falco, L., Padavattan, S., Rao, C., Geifman-Shochat, S., Liu, C.F., Davey, C.A.
Publication PMID: 31848352
doi 10.1038/s41467-019-13641-0
RCSB PDB 6K1K
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C H2A.X Homo sapiens P16104
Distal G H2A.X Homo sapiens P16104
H2B Proximal D canonical H2B Homo sapiens P06899
Distal H canonical H2B Homo sapiens P06899
DNA:
Chain Variant Length
I 601L 145
J 601L 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.