6JXD

Human nucleosome core particle with cohesive end DNA termini

Exp. Method X-ray
Resolution, Å 2.25
Release Date 2020-01-15
Update Date 2023-11-22
Authors Sharma, D., De Falco, L., Padavattan, S., Rao, C., Geifman-Shochat, S., Liu, C.F., Davey, C.A.
doi 10.1038/s41467-019-13641-0
Publication PMID: 31848352
Related structures
RCSB PDB 6JXD
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Homo sapiens P68431
Distal E canonical H3 Homo sapiens P68431
H4 Proximal B canonical H4 Homo sapiens P62805
Distal F canonical H4 Homo sapiens P62805
H2A Proximal C canonical H2A Homo sapiens P04908
Distal G canonical H2A Homo sapiens P04908
H2B Proximal D canonical H2B Homo sapiens P06899
Distal H canonical H2B Homo sapiens P06899
DNA:
Chain Variant Length
I 601_modified 147
J 601_modified 147

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

-40-30-20-10010203040-40-30-20-10010203040Coordinate X, ACoordinate Y, AH3H4H2AH2BDNA
Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.