6IRO

the crosslinked complex of ISWI-nucleosome in the ADP-bound state

Exp. Method EM
Resolution, Å 3.4
Release Date 2019-04-03
Update Date 2024-03-27
Authors Yan, L., Wu, H., Li, X., Gao, N., Chen, Z.
Publication PMID: 30872815
doi 10.1038/s41594-019-0199-9
RCSB PDB 6IRO
EMDB EMD-9720
Q-score 0.435
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
L ISWI chromatin-remodeling complex ATPase ISW1 P38144
DNA:
Chain Variant Length
I 601 146
J 601 146

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.