6GEJ

Chromatin remodeller-nucleosome complex at 3.6 A resolution.

Exp. Method EM
Resolution, Å 3.6
Release Date 2018-10-17
Update Date 2019-12-11
Authors Willhoft, O., Ghoneim, M., Lin, C.L., Chua, E.Y.D., Wilkinson, M., Chaban, Y., Ayala, R., McCormack, E.A., Ocloo, L., Rueda, D.S., Wigley, D.B.
Publication PMID: 30309918
doi 10.1126/science.aat7716
RCSB PDB 6GEJ
EMDB EMD-4395
Q-score 0.372
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P61830
Distal B canonical H3 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P61830
H4 Proximal D canonical H4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P02309
Distal C canonical H4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P02309
H2A Proximal E H2A.X Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P04911
Distal F H2A.X Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P04911
H2B Proximal G canonical H2B Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P02293
Distal H canonical H2B Saccharomyces cerevisiae (strain ATCC 204508 / S288c) P02293
Other proteins:
Chain Name UID
M Helicase SWR1 Q05471
R Actin-like protein ARP6 Q12509
S Vacuolar protein sorting-associated protein 71 Q03433
T RuvB-like protein 1 Q03940
U RuvB-like protein 2 Q12464
V RuvB-like protein 1 Q03940
W RuvB-like protein 2 Q12464
X RuvB-like protein 1 Q03940
Y RuvB-like protein 2 Q12464
DNA:
Chain Variant Length
I 601 154
J 601 154

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.