6FTX

Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

Exp. Method EM
Resolution, Å 4.5
Release Date 2018-08-08
Update Date 2018-10-17
Authors Sundaramoorthy, R., Hughes, A.L., El-Mkami, H., Norman, D.G., Ferreira, H., Owen-Hughes, T.
Publication PMID: 30079888
doi 10.7554/eLife.35720
RCSB PDB 6FTX
EMDB EMD-4318
Q-score 0.23
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Petromyzon marinus S4RAZ3
Distal E canonical H3 Xenopus laevis P02302
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus tropicalis Q28D68
Distal H canonical H2B Xenopus tropicalis Q28D68
Other proteins:
Chain Name UID
N Polyubiquitin-B P0CG47
O Polyubiquitin-B P0CG47
W Chromatin-remodeling ATPase P32657
DNA:
Chain Variant Length
I 601 159
J 601 160

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.