6DZT

Cryo-EM structure of nucleosome in complex with a single chain antibody fragment

Exp. Method EM
Resolution, Å 2.99
Release Date 2019-05-22
Update Date 2019-12-18
Authors Zhou, B.R., Yadav, K.N.S., Borgnia, M., Hong, J., Cao, B., Olins, A.L., Olins, D.E., Bai, Y., Zhang, P.
Publication PMID: 31127102
doi 10.1038/s41467-019-10247-4
RCSB PDB 6DZT
EMDB EMD-8938
Q-score 0.589
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Drosophila melanogaster P02299
Distal A canonical H3 Drosophila melanogaster P02299
H4 Proximal F canonical H4 Drosophila melanogaster P84040
Distal B canonical H4 Drosophila melanogaster P84040
H2A Proximal G canonical H2A Drosophila melanogaster P84051
Distal C canonical H2A Drosophila melanogaster P84051
H2B Proximal H canonical H2B Drosophila melanogaster P02283
Distal D canonical H2B Drosophila melanogaster P02283
Other proteins:
Chain Name UID
M scFv NA
N scFv NA
DNA:
Chain Variant Length
I 601 147
J 601 147

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor Q-score Local Resolution

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.