5WCU

Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5

Exp. Method X-ray
Resolution, Å 5.53
Release Date 2018-10-31
Update Date 2023-10-04
Authors Zhou, B.R., Jiang, J., Ghirlando, R., Norouzi, D., Sathish Yadav, K.N., Feng, H., Wang, R., Zhang, P., Zhurkin, V., Bai, Y.
Publication PMID: 29959925
doi 10.1016/j.jmb.2018.06.020
RCSB PDB 5WCU
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Drosophila melanogaster P02299
Distal E canonical H3 Drosophila melanogaster P02299
H4 Proximal B canonical H4 Drosophila melanogaster P84040
Distal F canonical H4 Drosophila melanogaster P84040
H2A Proximal C canonical H2A Drosophila melanogaster P84051
Distal G canonical H2A Drosophila melanogaster P84051
H2B Proximal D canonical H2B Drosophila melanogaster P02283
Distal H canonical H2B Drosophila melanogaster P02283
H1:
Chain HistoneDB Variant UID
U H5 P02259
V H5 P02259
DNA:
Chain Variant Length
I 601 164
J 601 167
S 601 164
T 601 167

H3

H4

H2A

H2B

H1

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.