5HQ2

Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle

Exp. Method X-ray
Resolution, Å 4.5
Release Date 2016-03-23
Update Date 2024-03-06
Authors Girish, T.S., McGinty, R.K., Tan, S.
Publication PMID: 26953260
doi 10.1016/j.jmb.2016.02.025
RCSB PDB 5HQ2
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
H2A Distal G canonical H2A Xenopus laevis P06897
H2B Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Guanine nucleotide exchange factor SRM1 P21827
M N-lysine methyltransferase SETD8 Q9NQR1
DNA:
Chain Variant Length
I 601_modified 73
J 601_modified 72

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.