4ZUX

SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome

Exp. Method X-ray
Resolution, Å 3.82
Release Date 2016-02-24
Update Date 2016-03-09
Authors Morgan, M.T., Haj-Yahya, M., Ringel, A.E., Bandi, P., Brik, A., Wolberger, C.
Publication PMID: 26912860
doi 10.1126/science.aac5681
RCSB PDB 4ZUX
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal A canonical H3 Xenopus laevis P84233
Distal E canonical H3 Xenopus laevis P84233
H4 Proximal B canonical H4 Xenopus laevis P62799
Distal F canonical H4 Xenopus laevis P62799
H2A Proximal C canonical H2A Xenopus laevis P06897
Distal G canonical H2A Xenopus laevis P06897
H2B Proximal D canonical H2B Xenopus laevis P02281
Distal H canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
U Ubiquitin carboxyl-terminal hydrolase 8 P50102
V Transcription and mRNA export factor SUS1 Q6WNK7
W SAGA-associated factor 11 Q03067
X Polyubiquitin-B P0CG47
Y SAGA-associated factor 73 P53165
Z Ubiquitin carboxyl-terminal hydrolase 8 P50102
a Transcription and mRNA export factor SUS1 Q6WNK7
b SAGA-associated factor 11 Q03067
c Polyubiquitin-B P0CG47
d SAGA-associated factor 73 P53165
e Ubiquitin carboxyl-terminal hydrolase 8 P50102
f Transcription and mRNA export factor SUS1 Q6WNK7
g SAGA-associated factor 11 Q03067
h Polyubiquitin-B P0CG47
i SAGA-associated factor 73 P53165
j Ubiquitin carboxyl-terminal hydrolase 8 P50102
k Transcription and mRNA export factor SUS1 Q6WNK7
l SAGA-associated factor 11 Q03067
m Polyubiquitin-B P0CG47
n SAGA-associated factor 73 P53165
DNA:
Chain Variant Length
I 601 145
J 601 145
S 601 145
T 601 145

H3

H4

H2A

H2B

DNA

Other


Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.