4LD9

Crystal structure of the N-terminally acetylated BAH domain of Sir3 bound to the nucleosome core particle

Exp. Method X-ray
Resolution, Å 3.306
Release Date 2013-08-14
Update Date 2013-09-18
Authors Arnaudo, N., Fernandez, I.S., McLaughlin, S.H., Peak-Chew, S.Y., Rhodes, D., Martino, F.
Publication PMID: 23934150
doi 10.1038/nsmb.2641
RCSB PDB 4LD9
Core histones in Nucleosome-like particles:
Side Chain HistoneDB Variant Taxa UID
H3 Proximal E canonical H3 Xenopus laevis P84233
Distal A canonical H3 Xenopus laevis P84233
H4 Proximal F canonical H4 Xenopus laevis P62799
Distal B canonical H4 Xenopus laevis P62799
H2A Proximal G canonical H2A Xenopus laevis P06897
Distal C canonical H2A Xenopus laevis P06897
H2B Proximal H canonical H2B Xenopus laevis P02281
Distal D canonical H2B Xenopus laevis P02281
Other proteins:
Chain Name UID
K Regulatory protein SIR3 P06701
L Regulatory protein SIR3 P06701
DNA:
Chain Variant Length
I 601 143
J 601 142

H3

H4

H2A

H2B

DNA

Other


Chain Bfactor

Aligned nucleosome coordinates

Nucleosome reference frame definition

DNA relative twist and local base step parameters

Sequence on X-axis is numbered relative to the dyad base pair.

Atomic contacts between nucleosomal entities.


Hover the mouse cursor on the barplot to show contact information. Oncogenic mutations of non-histone proteins in contact are highlighted.